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surmount-1 tirzepatide obesity nejm 2022 weight loss percent In the SURMOUNT-1 trial (published in NEJM in July 2022), adults with #obesity treated with weekly tirzepatide, a glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 receptor

Marsoni M251S
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Marco
Lowell, US
★★★★★ 5
Great product
Color: Multicolor, Color: Multicolor
I have three aggressive, chewing dogs that absolutely love these bones. I've had them for a couple of months and they have yet to break them or damage them. Lots of chewing left.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 28, 2026
T
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Tammy
Los Angeles, US
★★★★★ 5
Great for aggressive chewers!
Color: Orange - Maple Wood, Color: Orange - Maple Wood
Great for aggressive chewers!! My grand-dog loves it. It is slightly heavy, perfect for him. It definitely cleans his teeth. He plays with it all the time.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 6, 2026
L
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Literary Mom
Whiting, US
★★★★★ 3
My dog didn’t like it
Color: Orange - Maple Wood
Dog showed no interest at all
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 1, 2026
M
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Michael
Cuba, US
★★★★★ 4
They approve
Color: Multicolor
They seem to like them ok
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Reviewed in the United States on May 28, 2026
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Vito
Waukegan, US
★★★★★ 1
Was fun until it broke.
Color: Orange - Maple Wood, Color: Orange - Maple Wood
Broke on the third day after receipt while throwing in soft snow.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 1, 2026

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